superscan bone scan
Submitted by Dr Rishu Sangal Consultant. A superscan is an imaging appearance on a Tc-99m diphosphonate bone scan which occurs as a result of a high ratio of bone to soft tissue tracer accumulation.
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Love et al 2003.
. The overall incidence of superscan in different type of cancers was 13 806027. Gleason score was 54 and PSA at diagnosis was 419 μgl. In the normal patient both the osseous components of the skeletal system as well as the kidneys and bladder are visualized.
Quantitation using total counts recorded directly from the whole-body bone scan showed a significantly raised value in the superscan. In todays modern healthcare system bone scans are relatively quick inexpensive and widely available. Monday June 04 2012 bone scan skeletal metastasis superscan.
This bone scan of a patient with metastatic disease demonstrates the superscan phenomenon. The overall incidence of superscan in different type. A superscan is defined as bone scan planar imaging with diffuse increased skeletal tracer uptake relative to soft tissue combined with diminished or non-existent renal activity Brenner et al 2012.
Anterior and posterior images of a whole body bone scan of a 42-year-old male diagnosed at the age of 41 with adenocarcinoma of the prostate gland. Total of 6027 bone scans were examined in a 5-year period and out of which 80 cases were diagnosed as superscan. It may occur in widespread metastatic.
This is a report of bone scintigraphy demonstrating superimposed metastatic and metabolic superscan in a patient with prostate cancer who subsequently developed renal osteodystrophy. It is usually accompanied by absent or faint renal activity Sy et al 1975. Super bone scan is a special condition of extremely high bone uptake relative to soft tissue with absent renal radioactivity visualisation absent kidney sign1 About 4060 of the injected Tc-99m MDP is excreted in the urine2 Therefore significant renal and bladder radioactivity are normal in most scans.
Bone scan is part of the staging modality commonly used to evaluate bone metastasis. A bone scan in which there is excessive skeletal radioisotope uptake in relation to soft tissues along with absent or faint activity in the genitourinary tract is known as a superscan Apart from prostate cancer which is the most common condition associated with a superscan other malignancies like breast cancer lung cancer1234 can cause superscan. Superscan is a state of the art radiology and nuclear medicine group which offers patients the best technology in CT Nuclear Medicine X-Ray Ultrasound and Bone Mineral Densitometry.
This type of scan results in the. A superscan is defined as a bone scan which demonstrates markedly increased skeletal radioisotope. Technique A 20 mCi dose of 99m Tc-MDP is administered intravenously.
Whole-body bone scintigraphy bone scan using a 99m Tc-labelled pharmaceutical is one of the most commonly performed radionuclide examinations. Tracer uptake is so avid in bone that there is almost no renal excretion the kidneys are barely visualised. SuperScan is a multi-functional application designed as a.
Review by Andreea Matei on January 30 2013. This appearance has been associated with two main pathological groups. Whole-body images of the skeleton are obtained 3 hours after tracer administration.
However a primary concern are false negatives associated with bone scans where diffuse metastasis is. A 72-year-old man with a history of metastatic prostate cancer is referred for a bone scan because of pain in the left shoulder and lower neck. In the 5-year study period we evaluated whole body bone scans of 6027 patient with underlying malignancy out of which 80 patients were reported as superscans and overall incidence of superscan appearance in different type of cancer patients was 13 Sixty-three 787 were men and 17 212 were women The mean age of the patients was 584 14 years SD and.
Bone scans myocardial perfusion studies MIBIstress tests thyroid uptake studies renal studies HIDA lymphoscintigraphy and sentinel node mapping VQ scans. Although a superscan can occur in a broad range of conditions both malignant and metabolic the vast majority are due to high volume. Qualitative comparison showed patterns of avid bone uptake with diminished visualization of kidney and bladder activity in the superscan group and normal scans in the control and prostate patient groups.
Superscan offers the following services to patients. Superscan in Bone Scintigraphy BS is defined as increased radiotracer uptake in the axial and appendicular skeleton with negligible soft tissue and renal radiotracer uptake 1. Start scanning TCP ports and ping IP addresses.
Prostate cancer 4680 was the most common cause of superscan appearance followed by breast cancer 1080. Nuclear Medicine eg. The superscan effect presents a technical challenge in the evaluation of lesions on bone scans in prostate cancer clinical trials.
Superscan pattern is also seen in Pagets disease renal osteodystrophy and non prostatic cancers by such as colon breast lung leukemia lymphoma waldenstroms. In bone imaging the term superscan has been used to describe the appearance of high skeletal uptake of radionuclide combined with low background activity Osmond etal 1975. Total of 6027 bone scans were examined in a 5-year period and out of which 80 cases were diagnosed as superscan.
Superscans on bone scintigraphy have been described mostly in metastatic and metabolic bone diseases with different patterns and appearances of radiotracer uptake. Superscan provides patients with highest quality pictures at the lowest possible radiation dose and is also home to the worlds lowest radiation dose and. A super bone scan may result from a widespread.
A superscan is a bone scan which exhibits diffuse skeletal uptake of the radiopharmaceutical agent with little to no uptake within soft tissue including the kidneys and bladder. A bone scan with diffused increased skeletal tracer uptake relative to soft tissue combined with faint renal activity is known as a superscan. A superscan is a term given to the appearances on a nuclear bone scan when bony uptake of Tc99m disphosponate is so profound that the usual physiological uptake observed in the kidneys is no longer apparent.
Intense osteoblastic activity in the bones causes diminished renal and background soft tissue uptake. Up to 10 cash back His Tc-99m PSMA images revealed diffuse bone infiltration in a pattern mimicking a bone scan.
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